Essentials of Free Radical Biology and Medicine

The book (i) blends basic and clinical sciences needed to effectively demonstrate the importance of the field; (ii) includes full-color illustrations to facilitate the understanding of the essential concepts; (iii) cites references mostly ...

Essentials of Free Radical Biology and Medicine

Author: Robert Z. Hopkins

Publisher:

ISBN: 9781680560008

Page:

View: 717

Written in an accessible style and consistent format, "Essentials of Free Radical Biology and Medicine" takes a unique approach to integrating the fundamental principles with high quality cutting-edge research discoveries, and the basic bioscience with clinical medicine so as to provide the reader a comprehensive picture of the field in a concise manner. The book (i) blends basic and clinical sciences needed to effectively demonstrate the importance of the field; (ii) includes full-color illustrations to facilitate the understanding of the essential concepts; (iii) cites references mostly from highly influential journals to ensure the top quality of the information; (iv) uses self-assessment questions and glossary to enhance the assimilation of the cutting-edge knowledge; and (v) serves as a valuable reference or textbook for students, faculty, and other professionals in the fields of biology, pharmaceutical science, biomedical science, and clinical medicine.

Free Radicals in Biology and Medicine

New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers.

Free Radicals in Biology and Medicine

Author: Barry Halliwell

Publisher: Oxford University Press, USA

ISBN: 0198717482

Page: 896

View: 913

Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Essentials of Spinal Cord Injury Medicine

Journal of Bioenergetics and Biomembranes. 2016 Apr 18;48(2):169-174 de
Zwart LL, Meerman JH, Commandeur JN, Vermeulen NP. Biomarkers of free
radical damage. Free Radical Biology & Medicine. 1999;26(1–2):202-226 Banes
AJ, ...

Essentials of Spinal Cord Injury Medicine

Author: Yannis Dionyssiotis

Publisher: BoD – Books on Demand

ISBN: 1789232481

Page: 166

View: 861

Spinal cord injury is a severe condition leading to serious neurological dysfunctions and changes a person's life in a sudden way. Understanding the pathophysiology of spinal cord injury will improve the prognosis and reintegration to the society of spinal cord-injured subjects. The book Essentials in Spinal Cord Injury Medicine includes seven chapters with valuable information addressing hot topics related to spinal cord injury, ranging from pathophysiology, nontraumatic spinal cord injury, complications to exoskeletons, and research therapies with mesenchymal stem cells. The book could be a valued reference for physiatrists, neurosurgeons, orthopedic surgeons, neurologists and physical therapists.

Issues in Discovery Experimental and Laboratory Medicine 2011 Edition

Free Radical Biology & Medicine, 2009;47(12):1742-52). For more information,
contact J.S. ... cell. death. A new study, 'Iron-mediated oxidative stress plays an
essential role in ferritin-induced cell death,' is now available. “Previously, we
have ...

Issues in Discovery  Experimental  and Laboratory Medicine  2011 Edition

Author:

Publisher: ScholarlyEditions

ISBN: 1464963509

Page: 3453

View: 454

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Discovery, Experimental, and Laboratory Medicine. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Discovery, Experimental, and Laboratory Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Essential Amino Acids Advances in Research and Application 2011 Edition

Sliskovic and colleagues published their study in Free Radical Biology and
Medicine (Analysis of the mechanism by which ... For additional information,
contact I. Sliskovic, Wayne State University, Sch Medical, Dept. of Obstet &
Gynecol, CS ...

Essential Amino Acids  Advances in Research and Application  2011 Edition

Author:

Publisher: ScholarlyEditions

ISBN: 1464923191

Page: 264

View: 145

Essential Amino Acids: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Essential Amino Acids. The editors have built Essential Amino Acids: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Essential Amino Acids in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Essential Amino Acids: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Essential Oil Bearing Grasses

Free Radical Biological Medicine 23, 712–719. Helander, I.M., Alakomi, H., Latva
-Kala, K., Mattila-Sandholm, T., Pol, I., Smid, E., Gorris, L.G.M., von Wright, A.,
1998. Characterization of the action of selected essential oil components on ...

Essential Oil Bearing Grasses

Author: Anand Akhila

Publisher: CRC Press

ISBN: 9780849378584

Page: 262

View: 770

When enjoying a southeast asian soup or cup of herbal tea, we are really savoring the flavor of lemongrass. Similarly, the sweet aroma of mosquito-repelling lotions comes from the citronella oil present in them. Fine perfumes, candles, and herbal pillows with the pleasing smell of rose are often in fact scented with palmarosa. Providing an in-depth look at their history and production, Essential Oil Bearing Grasses: The genus Cymbopogon provides a comprehensive review of these economically important grasses. A detailed examination of chemical constituents and market trends, the book explores the cosmetic, medicinal, and nutritional uses of the plant. It covers the botany, taxonomy, chemistry, and biogenesis of the oils, and their extraction and analytical methods, biotechnology, storage, legislation, and trade. Highlighting industrial uses for the grasses in this genus, the book also includes coverage of the physiological and ecophysiological considerations. It presents a comprehensive overview of most of the cultivated and wild species of cymbopogons. Featuring contributions from a team of international experts, the book describes the considerable ethno-botanical, phytochemical, and pharmacological knowledge associated with the multidimensional uses of the oils. It provides a complete industrial profile that includes market size, geographical sources, export and import data, and industry uses. Its pages offer an invaluable resource for research, cultivation, marketing, or product development of Cymbopogon.

Essential Herbs and Natural Supplements

Phytomedicine 10.4 (2003): 271–285. ... Phytomedicine 17.7 (2010): 494–9. Bae
H et al. ... activity through modulation of the redox-sensitive transcription factors
Nrf2 and NF-Œ∫B. Free Radical Biology and Medicine 53.7 (2012): 1421–30.

Essential Herbs and Natural Supplements

Author: Lesley Braun

Publisher: Elsevier

ISBN: 0729586537

Page:

View: 564

Essential Herbs and Natural Supplements is an evidence-based quick reference guide. This go-to resource is essential for safe and effective clinical recommendations of herbal medicines and natural supplements. It provides current, evidence-based monographs on the 50 most commonly used herbs, nutrients and food supplements. It emphasises safe practice with strategies to prevent adverse drug reactions, guidelines in assessing benefit, risk and harm and the evaluation of research. 50 evidence-based monographs on the most used herbs and natural supplements Up-to-date evidence on the latest research impacting on herbal and natural medicine by top leaders within the fields of Pharmacy, Herbal Medicine and Natural Medicine Considerations of herbs and natural supplements in pregnancy

Free Radicals in Biology and Medicine

Whilst their production by phagocytic cells is, of course, essential for the eradication of invading pathogens, and the capacity of selected chemotherapeutic agents to generate such species in specific `target' cells is well known in cancer ...

Free Radicals in Biology and Medicine

Author: Okezie I. Aruoma

Publisher: IOS Press

ISBN: 9781586036836

Page: 272

View: 661

"Oxidative stress and inflammatory cell death / tissue damage have been implicated in a wide array of human diseases, including cancer, neurodegenerative diseases, diabetes, inflammatory joint diseases,; cardiovascular dysfunctions as well as ageing. Oxidative stress mediates the activation of transcription factors such as NF?B that, in turn, induce the transcription of certain genes promoting cytokine production. Release of these cytokines results in the enhancement of inflammatory responses and activation of endothelial cells in distant organs. The inflammatory cascade is then triggered by the induction of adhesion molecules and the generation of cytokines and other inflammatory mediators. Given that reactive oxygen and nitrogen species (ROS and RNS respectively) generated by infiltrated neutrophils into distant organs act directly as noxious agents reacting with molecular components, thereby enhancing inflammatory processes and therefore influencing cell viability, ROS and RNS have become potential therapeutic targets for prophylactic biofactors. Whilst their production by phagocytic cells is, of course, essential for the eradication of invading pathogens, and the capacity of selected chemotherapeutic agents to generate such species in specific `target' cells is well known in cancer research, the novel therapeutic actions and potential mechanisms of action of ozone as a microbicidal agent in clinical dentistry are now being advocated. The focus of this publication prominently encompasses the pivotal roles of ROS and RNS in the pathogenesis of many clinical conditions (together with their involvement in the ageing process of lower (yeast) cells, and higher organisms including plants), and discusses the potential applications of dietary-derived antioxidants to interfere with the biomolecular mechanisms of these processes and hence offer realistic therapeutic or prophylactic potentials."

Imino Acids Advances in Research and Application 2013 Edition

Nebraska,. Lincoln: Proline. dehydrogenase. is. essential. for. proline. protection.
against. hydrogen. peroxide-induced. cell. death. By a News ... (Elsevier - www.
elsevier.com; Free Radical Biology & Medicine - http: //www . elsevier ...

Imino Acids   Advances in Research and Application  2013 Edition

Author:

Publisher: ScholarlyEditions

ISBN: 1481676601

Page: 178

View: 540

Imino Acids—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Imino Acids—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Imino Acids—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Nutrition and Epigenetics

OXYGEN BIOLOGY AND MEDICINE Through evolution, oxygen—itself a free
radical—was chosen as the terminal ... It has been established that low levels of
oxygen free radicals and reactive oxygen species are essential for some cell ...

Nutrition and Epigenetics

Author: Emily Ho

Publisher: CRC Press

ISBN: 1482203820

Page: 422

View: 987

Nutrition and Epigenetics presents new information on the action of diet and nutritional determinants in regulating the epigenetic control of gene expression in health and disease. Each chapter gives a unique perspective on a different nutritional or dietary component or group of components, and reveals novel mechanisms by which dietary factors modulate the epigenome and affect development processes, chronic disease, and the aging process. This pivotal text: Documents the epigenetic effect of antioxidants and their health benefits Adds to the understanding of mechanisms leading to disease susceptibility and healthy aging Illustrates that the epigenetic origins of disease occur in early (fetal) development Synthesizes the data regarding nutrient and epigenomic interactions Nutrition and Epigenetics highlights the interactions among nutrients, epigenetics, and health, providing an essential resource for scientists and clinical researchers interested in nutrition, aging, and metabolic diseases.

Free Radical Biology in Digestive Diseases

Free Radical Biology Naito Y, Suematsu M, YoshikawaT (eds): Free Radical
Biology in Digestive Diseases. Front Gastrointest Res. Basel, Karger, 2011, vol
29, pp 1–11 Free Radicals and Lipid Peroxidation Etsuo Niki Kyoto Prefectural
University of Medicine, Kyoto, National Institute ... modify biologically essential
molecules such as proteins and DNA bases Free Radical Biology Free Radicals
and Lipid ...

Free Radical Biology in Digestive Diseases

Author: Yuji Naito

Publisher: Karger Medical and Scientific Publishers

ISBN: 380559609X

Page: 176

View: 553

There is a growing body of experimental and clinical data to suggest that the organs of the digestive system may be subjected to considerable oxidative stress associated with acute and chronic inflammation. Although inflammation and ischemia play a key role in producing oxygen-derived free radicals in the digestive tract, the contribution of other factors, such as transition metal imbalances, lipid and glucose metabolic disturbance, and the interaction with gaseous molecules including nitric oxide and carbon monoxide, has also been suggested. Recent studies have demonstrated that several biomarkers indicating oxidative stress-mediated damage may help in monitoring the degree of disease and planning the design of new therapeutic strategies. In addition, recent advances in 'omics' research (genomics, proteomics, metabolomics, etc.) may bring a breakthrough in the field of gastroenterology and hepatology: Several molecular targets for oxidative stress have been presented by the 'omics'. This book includes up-to-date reviews on the relevant issues in free radical biology in a combination with expert basic research reviews and clinical aspects in gastroenterology and hepatology. Providing information about new molecular targets for the treatment or prevention of digestive diseases, this book should be read by clinical and basic researchers in gastroenterology and hepatology.

Bio Assays for Oxidative Stress Status

This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, Free Radical Biology & Medicine.

Bio Assays for Oxidative Stress Status

Author: W.A. Pryor

Publisher: Elsevier

ISBN: 0080929923

Page: 296

View: 347

This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, Free Radical Biology & Medicine. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal, over many months. This is the first time that all of these expert contributions are presented in one place. Reliable methods for measuring OSS in organisms are essential. These would, amongst other things, offer applications as early warning signals for cancer and heart disease - eventually giving a range of measurable oxidation products best related to any given disease state. Additional observations relevant to OSS include: how much do measures of OSS vary in a group of humans? Does OSS decrease as a result of life-change factors and does it increase with age? With disease? With stress? Can a non-invasive, reliable, reputable measure of OSS be identified? This informative book provides the reader with the latest status of studies into OSS, currently used examples of BOSS, and answers to at least some of the questions posed above.

Free Radicals and Iron

This concise monograph describes a variety of important reactions of iron in biological free-radical reactions.

Free Radicals and Iron

Author: Martyn C. R. Symons

Publisher: Oxford University Press on Demand

ISBN:

Page: 242

View: 269

This concise monograph describes a variety of important reactions of iron in biological free-radical reactions. It presents both a chemical and a biochemical perspective of the topic, but at the same time unifies ideas where possible. Iron plays a key role in biological life processes, as acatalayst enabling us to use oxygen to generate the heat and chemical energy that drives life. When iron is not properly controlled within the body it can cause damage by making free radicals. The authors present a chemical and biomedical perspective of how reactions of iron complexes and freeradicals may contribute to human health and disease, especially in reactions of oxygen and hydrogen peroxide.

Micronutrients and Brain Health

OXYGEN BIOLOGY AND MEDICINE Through evolution, oxygen—itself a free
radical—was chosen as the terminal electron acceptor for ... Other oxygen-
derived free radicals such as superoxide anion or hydroxyl radicals formed
during metabolism or by ionizing ... Their proper balance is essential for ensuring
healthy aging.

Micronutrients and Brain Health

Author: Lester Packer

Publisher: CRC Press

ISBN: 9781420073522

Page: 460

View: 921

Micronutrients and Brain Health addresses cutting-edge research related to processes of oxidative stress that affect brain function, an area of increasing significance for those concerned and involved with public health and translational medicine. Edited by four leading micronutrient researchers, the book brings together the investigative work of more than 70 leading researchers from across the world. Chapters identify brain-specific micronutrients that support function as well as the molecular mechanisms underlying their neuroprotectant activity. These explore age-related metabolic pathways, mitochondrial nutrients, neurodegeneration and micronutrients, cell signaling, and neuronal functions. General chapters are included on brain structure, function, and metabolism, while several other chapters are devoted to the role of specific micronutrients. The book explores how brain micronutrients are found to be both metabolic and redox regulators, thereby establishing a cross-talk between the major pathways involved in modulation of cell signaling and gene expression. Specific areas of research covered include: Uses of nutritional interventions to target age-related neuronal and behavioral deficits Effects of various micronutrients on Alzheimer’s disease, including lipoic acid, green tea, and Ginkgo biloba extracts Nutrients specific to essential mitochondrial functions Cognitive and behavioral consequences of iron deficiency with specific emphasis on women of reproductive age Omega-3 fatty acids and their relation to brain function in the elderly Challenges inherent in the development of neuroprotective-neurorescue drugs This book belongs to the groundbreaking CRC Press Series on Oxidative Stress and Disease. The series now includes more than two dozen volumes that address increasing evidence regarding the multiple ways that oxidative stress initiates and accelerates disease mechanisms. Most importantly, this book, like the series, offers invaluable information regarding nutritional and lifestyle choices, and pharmaceutical interventions that can be employed to prevent, control, and even ameliorate disease processes attributed to oxidative stress.

Processing and Nutrition of Fats and Oils

Free Radical Biology and Medicine, 9,315–325. Stadtman, E.R. (1993) Oxidation
of free ... Journal of Dairy Science, 84, 2440–2449. Tipsrisukond, N., Fernando,
L.N., and Clarke, A.D. (1998) Antioxidant effects of essential oil and oleoresin ...

Processing and Nutrition of Fats and Oils

Author:

Publisher: John Wiley & Sons

ISBN: 1118528786

Page: 276

View: 264

Processing and Nutrition of Fats and Oils reviews current and new practices of fats and oils production. The book examines the different aspects of fats and oils processing, how the nutritional properties are affected, and how fats interact with other components and nutrients in food products. Coverage includes current trends in the consumption of edible fats and oils; properties of fats, oils and bioactive lipids; techniques to process and modify edible oils; nutritional aspects of lipids; and regulatory aspects, labeling and certifications of fats and oils in foods.

Andreoli and Carpenter s Cecil Essentials of Medicine E Book

THE BIOLOGY OF AGING The relatively static nature of ... The free radical theory
of aging proposes that oxidative metabolism results in an excess of highly
reactive byproducts, called oxygen free radicals, which damage proteins, DNA,
and ...

Andreoli and Carpenter s Cecil Essentials of Medicine E Book

Author: Ivor Benjamin

Publisher: Elsevier Health Sciences

ISBN: 1437726739

Page: 1312

View: 827

Students, residents, and instructors swear by Andreoli and Carpenter’s Cecil Essentials of Medicine because it presents just the right amount of information, just the right way. Edited by the late Thomas E. Andreoli, MD as well as Ivor Benjamin, MD, Robert C. Griggs, MD, and Edward J. Wing, MD, it focuses on core principles and how they apply to patient care, covering everything you need to know to succeed on a medical rotation or residency. Masterful editing and a user-friendly full-color design make absorbing and retaining information as effortless as possible. New chapters on "Pre- and Post-Operative Care" and "Palliative Care," plus the integration of molecular biology and other new horizons in medicine, familiarize you with the most current clinical concepts. An expanded International Editorial Board provides increased input from respected practitioners worldwide. Excellent images and clinical photographs vividly illustrate the appearance and clinical features of disease. Masterful editing and a user-friendly full-color design make absorbing and retaining information as effortless as possible.

Trace Elements and Other Essential Nutrients

Clinical , Biochemical , and Nutritional Aspects of Trace Elements . Alan R . Liss ,
Inc . N . Y . , 1982 . Aust , S . D , White , B . C : Iron Chelation Prevents Tissue
Injury Following Ischemia . Advances in Free Radical Biology and Medicine Vol .

Trace Elements and Other Essential Nutrients

Author: David L. Watts

Publisher:

ISBN:

Page: 182

View: 312

Huntington Disease New Insights for the Healthcare Professional 2011 Edition

The publisher's contact information for the journal Free Radical Biology and
Medicine is: Elsevier Science Inc., 360 Park Avenue South, New York, NY 10010-
1710, USA. (ZOlOAUG 17) Widener University, Chester: Ripples From a Stone ...

Huntington Disease  New Insights for the Healthcare Professional  2011 Edition

Author:

Publisher: ScholarlyEditions

ISBN: 1464904375

Page: 54

View: 512

Huntington Disease: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Huntington Disease in a concise format. The editors have built Huntington Disease: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Huntington Disease in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Huntington Disease: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Nuclear Physics Methods and Accelerators in Biology and Medicine

Fourth International Summer School on Nuclear Physics Methods and
Accelerators in Biology and Medicine American Institute of Physics ... Free
Radicals, Life and Radiation Ryszard Krzyminiewski Division of Medical Physics,
Faculty of Physics, Adam Mickiewicz ... This is called metabolism and it is, of
course, essential.

Nuclear Physics Methods and Accelerators in Biology and Medicine

Author: American Institute of Physics

Publisher: Amer Inst of Physics

ISBN:

Page: 309

View: 619

These proceedings are a collection of manuscripts of the lectures given at the Fourth International Summer School on Nuclear Physics Methods and Accelerators in Biology and Medicine. They provide a broad up-to-date review of the current knowledge and methods of Nuclear Physics and Particle Accelerators and their applications in medicine and biology. The material here will be of huge interest to university students of engineering, physics, medicine, and biology.