Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online.
Author: Books Llc
Publisher: Books LLC, Wiki Series
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 29. Chapters: Truth drug, Primidone, Barbiturate, Phenobarbital, Pentobarbital, Amobarbital, Secobarbital, Blue 88, Tuinal, Butalbital, Barbituric acid, Methohexital, Hexobarbital, Barbiturate overdose, Barbiturate dependence, Methylphenobarbital, Allobarbital, Butabarbital, Brallobarbital, Corvalol, Dexamyl, Proxibarbital, Aprobarbital, Bucolome, Talbutal, Butallylonal, Valofane, Crotylbarbital, Benzylbutylbarbiturate, Metharbital, Reposal, Cyclopal, Propallylonal, Benzobarbital, Hexethal, Narcobarbital, Alphenal, Barbexaclone, Febarbamate, Nealbarbital, Sigmodal, Prazitone, Eterobarb, Carbubarb, Enallylpropymal, Phetharbital, Spirobarbital, Brophebarbital, Butobarbital, Heptabarbital, Vinylbital, Cyclobarbital, Vinbarbital, Thiobarbituric acid, Ethallobarbital, Desbutal. Excerpt: Primidone is an anticonvulsant of the pyrimidinedione class, the active metabolites of which, phenobarbital (major) and phenylethylmalonamide (PEMA) (minor), are also anticonvulsants. It is used mainly to treat complex partial, simple partials, generalized tonic-clonic seizures, myoclonic, akinetic seizures and since the 1980s it has been a valuable alternative to propranolol in the treatment of essential tremor. Unlike other anticonvulsants such as carbamazepine and valproic acid, primidone is rarely used in the treatment of bipolar disorder or any other psychiatric problem. It is also not widely used in treatment of neuropathic pain, trigeminal neuralgia, or migraine. Primidone has been occasionally used to treat long QT syndrome, cerebral palsy, and athetosis. Primidone was once a mainstay anticonvulsant in the treatment of partial and generalized seizures and was the treatment of choice for secondarily generalized seizures originating in the temporal lobes, especially when combined with phenytoin, but by the early 1980s, carbamazepine had surpassed...