Theories of Immune Networks

For a long time, immunology has been dominated by the idea of a simple linear cause-effect relationship between the exposure to an antigen and the production of specific antibodies against that antigen.

Theories of Immune Networks

Author: Henri Atlan

Publisher: Springer Science & Business Media

ISBN: 3642839355

Page: 117

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For a long time, immunology has been dominated by the idea of a simple linear cause-effect relationship between the exposure to an antigen and the production of specific antibodies against that antigen. Clonal selection was the name of the theory based on this idea and it has provided the main concepts to account for the known features of the immune response. More recently, immunologists have discovered a wealth of new facts, in the form of different regulatory cells (helpers, suppressors, antigen presenting cells), genetic determinations of immune responses such as those involved in graft re jections, different molecular structures responsible for intercellular interactions such as interleukins, cytokins, idiotype-antiidiotype recognition and others. While furthering our understanding of the local interactions (molecular and cellular) in volved in the immune response, these discoveries have led to a questioning of the simplicities of the classical clonal selection theory. It is clear today that every single immune response is a cooperative phenomenon involving several different molecular and cellular interactions taking place in a coupled manner. In addition, cross reactivity to different antigens has shown that responses of the whole im mune system to different antigens are not completely isolated from one another and that the history of encounters with different antigens plays a crucial role in the maturation of the whole system. Thus, problems of complexity, generation of di versity and self-organization have entered the field of immunology.

1997 27th International Symposium on Multiple Valued Logic

( 4 ) H. Atlan , and I.R. Cohen , eds . , Theories of Immune Networks , Springer -
Verlag , Berlin , 1989 . ( 5 ) A.S. Perelson , “ Immune network theory ” , Immunol .
ogy Review , no . 10 , pp . 5-36 , 1989 . ( 6 ) T. Ikegami , “ Dynamical behavior of ...

1997 27th International Symposium on Multiple Valued Logic

Author:

Publisher: IEEE

ISBN: 9780818679100

Page: 293

View: 560

Proceedings of the May 1997 symposium. MVL researchers from around the world present 37 papers in sessions on algebra, device technology, circuits, fuzzy logic, logic design, philosophical aspects, spectral techniques, testing and fault simulation, and applications. In addition, three invited addresses--recent developments in DNA- computing; many-valuedness and uncertainty; and ternary decision diagrams (survey)--further illustrate the diverse nature of multiple-valued research. Topics of the papers include finding composition trees for multiple-valued functions; hyperclones on a finite set; and multiple-valued logic as a programming language. No index. Annotation copyrighted by Book News, Inc., Portland, OR.

Current Catalog

9012740 Theories of immune networks / H. Atlan , I.R. Cohen ( eds . ) ... Immune
System - physiology - congresses 2 . ... 9010244 Theory and practice of
histological techniques / edited by John D. Bancroft , Alan Stevens ; foreword by
David R.

Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

ISBN:

Page:

View: 328

First multi-year cumulation covers six years: 1965-70.

Complex Systems

( 23 ) N. K. Jerne , “ The Immune System , ” Sci . Am . , 1 ( 1973 ) 52-60 . [ 24 ] Z.
Grossman , “ The Concept of Idiotypic Network : Deficient or Premature ? " in
Theories of Immune Networks , edited by H. Atlan and I. R. Cohen ( Springer -
Verlag ...

Complex Systems

Author:

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Workshop on stochastic modelling in biology

... I . R . ( 1989 ) Natural id - anti - id networks and the immunological homunculus
, in : Theories of Immune Networks , eds . Atlan , H . and Cohen , I . R . , Springer
Verlag , Heidelberg Paul W . E . ( 1989 ) The immune system : An introduction ...

Workshop on stochastic modelling in biology

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Sixth Brazilian Symposium on Neural Networks

Introduction The vertebrate immune system has several useful mechanisms from
the viewpoint of of information processing . Among the many immunological
models , we can stress the immune network theory [ 6 ] and the clonal selection
and ...

Sixth Brazilian Symposium on Neural Networks

Author: Carlos H. C. Ribeiro

Publisher: IEEE

ISBN:

Page: 296

View: 758

With 46 papers from the November 2000 conference in Rio de Janeiro, this volume represents the work of computer scientists, artificial intelligence researchers, and engineers from around the world. They address issues like neurosymbolic processing, neural computation, scalars, CDMA and TCMA based neural nets, genetic algorithms, PARMA modeling, hierarchical neural models, web text mining, inverse kinematics problems in robot control, image compression, and morphological rules of similarity. Also included are abstracts of 24 other papers, originally written in Portugese or Spanish. Name index only. Annotation copyrighted by Book News, Inc., Portland, OR.

Studia biophysica

262 Book Review H . ATLAN , I . R . COHEN ( Eds . ) : Theories of Immune
Networks Springer - Verlag Berlin Heidelberg New York 117 Pages , 23 Figures ,
Format 17 cm x 24 cm price : DM 85 , - - The fact that the immunological reaction
of a ...

Studia biophysica

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Network

C - 21 1197 - 206 [ 12 ] Kauffman S 1971 Gene regulation networks : theory for
their global structure and behaviors ... of the immune cellular response by small
neural networks Theories of the Immune Networks ed H Atlan and I R Cohen ...

Network

Author:

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Toward Micro mechatronics in 21st Century

References ( 1 ) Goran Moller ( ed ) , Immunological Memory , Immunological
Reviews , No150 ( 1996 ) O( 2 ) Stephan ... I . R . Cohen ( ed ) : ” Theories of
Immune Networks ” , Springer - Verlag ( 1989 ) ( 5 ) William F . Loamis , An essay
on the ...

Toward Micro mechatronics in 21st Century

Author:

Publisher: Institute of Electrical & Electronics Engineers(IEEE)

ISBN: 9780780335967

Page: 276

View: 267

The major focus of this symposium is on strategic initiatives for the promotion of micro machine and human science technologies.

Cell to Cell Signalling

to immune network theory . In Theoretical Immunology , Part Two ( ed . A . S .
Perelson ) , pp . 321 - 43 . Addison - Wesley , Redwood City , CA . Segel , L . A .
and Perelson , A . S . ( 1989a ) A paradoxical instability caused by relatively short
 ...

Cell to Cell Signalling

Author: A. Goldbeter

Publisher:

ISBN:

Page: 647

View: 916

"These papers were first presented at the NATO Advanced Research Workshop 'Theoretical Models for Cell to Cell Signalling' held in Knokke-Zoute, Belgium, during September 1988. The Workshop was further supported by the Commission of the European Communities."--Preliminary page.

Bibliography of Agriculture

774524 Cellular immunity in chicks expressing fibrosarcomatous liver tumor
following embryo infection with subgroup A Rous ... 774439 IMMUNE SYSTEM --
COMPUTER SIMULATION-CONGRESSES Theories of immune networks
776071 ...

Bibliography of Agriculture

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The Generation of Diversity

The Concept of Idiotypic Network : Deficient or Premature ? In Theories of
Immune Networks , ed . H . Atlan and I . R . Cohen , 38 – 52 . Berlin :
SpringerVerlag . - 1993 . Cellular Tolerance as a Dynamic State of the Adaptable
Lymphocyte .

The Generation of Diversity

Author: Professor of Philosophy Emeritus Zoltan Kohn Professor Emeritus of Medicine Alfred I Tauber

Publisher:

ISBN:

Page: 508

View: 673

In recent decades immunology has been one of the most exciting--and successful--fields of biomedical research. Over the past thirty years immunologists have acquired a detailed understanding of the immune system's unique recognition mechanism and of the cellular and chemical means used to destroy or neutralize invading organisms. This understanding has been formulated in terms of the clonal selection theory, the dominant explanation of immune behavior. That story is the subject of The Generation of Diversity. A major problem for immunologists had long been to determine how cells of the immune system could produce millions of distinct antibodies--and produce them on demand. The clonal selection theory explains that cells with genetic instructions to produce each antibody exist in the body in small numbers until exposure to the right molecule--the antigen--triggers the selective cloning that will reproduce exactly the cell needed. But how can so many different antibody-producing cells be generated from such limited genetic material? The solution to this question came from new applications of molecular biology, and, as the authors argue, the impact of the new techniques changed both the methods and the concepts of immunology. The Generation of Diversity is an intellectual history of the major theoretical problem in immunology and its resolution in the post-World War II period. It will provide for immunologists essential background for understanding the conceptual conflicts occurring in the field today.

Scientific Activities

Bülthoff , H.H. and S. Edelman : Evaluating object recognition theories by
computer graphics psychophysics . ... De Boer , R.J. , A.U. Neumann , A.S.
Perelson , L.A. Segel and G. Weisbuch : Recent approaches to immune networks
. In : Proc .

Scientific Activities

Author: Mekhon Ṿaitsman le-madaʻ

Publisher:

ISBN:

Page:

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Ecological Physical Chemistry

Network Regulation of Autoimmunity : An Automaton Model . J . Autoimmunity , 2
, 1989 , pp . 613 - 625 . 15 ) H . Atlan and S . H . Snyder . Simulation of the
Immune Cellular Response by Small Neural Networks , in : Theories of Immune ...

Ecological Physical Chemistry

Author: C. Rossi

Publisher: Elsevier Science Limited

ISBN:

Page: 651

View: 652

A great debate has arisen about the necessity to distinguish between different physical chemistry approaches for investigating the behavior of natural systems. On the one side, it is necessary to recognize that the use of time-reversible classical and quantum physical chemistry approaches for studying molecular systems yields a big improvement in man's knowledge. On the other hand it is imperative to have new approaches, new time-irreversible theories, able to describe these relationships. Ecological physical chemistry is a new transdisciplinary field of study that addresses the relationships between complex molecular systems and/or organisms. This new field goes beyond the normal conceptions of scientific disciplines and tries to integrate and harmonize many different disciplinary perspectives. Ecological physical chemistry thus, wants to develop new theories and strategies for investigating the complexity of nature, and the present book is the first report on this intriguing new scientific discipline.

Immune Networks

NETWORK INTERACTIONS IN THE GENERATION OF THE T - HELPER CELL
REPERTOIRE We will start by assuming ... low affinity interactions with self that is
so often involved in theories dealing with the generation of the T - cell repertoire .

Immune Networks

Author: Constantin A. Bona

Publisher:

ISBN:

Page: 395

View: 227

Artificial Life

Multi - level Selection and Immune Networks : Preliminary Discussion of an
Abstract Model Tom Lenaerts , Anne ... is the number of ways of the immune
network theory proposed inability of artificial models to construct functional hier
by N . K ...

Artificial Life

Author:

Publisher:

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Consists of the proceedings of: 1987, Interdisciplinary Workshop on the Synthesis and Simulation of Living Systems; 1990-1992, Artificial Life Workshop; 1994-1996, International Workshop on the Synthesis and Simulation of Living Systems; 1998- , International Conference on Artificial Life.